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Advice about TB Tests

Berkeley Parents Network > Advice > Advice about Health > Advice about TB Tests


April 1999

Our daughter has tested positive (14mm) to a TB skin test. We are both negative and can't figure out where she could have been exposed. She does not have TB and a chest X-Ray was normal. We are even wondering if this is a false positive, which are not uncommon. It has been recommended that she take the 6 month course of Isoniazid. Has anyone had this experience or treated active TB with this drug? How did your child fare? Any tips on getting two large pills down a 5 year old everyday? Thanks.


About ten years ago I also tested positive for TB (skin test) but my chest x-ray was fine. I did not have TB, but my doctor at that time (a new grad from medical school I think) prescribed some pills for me which I was told would have some side effects with the liver. I never took those pills. My pediatrician who had worked in Asia told me that many people from Asia had (chicken pox? I don't remember ) immunization shots when when they were young -- which is exactly my case-- and would test positive on the skin test even though they do not have TB. I wonder if your daughter's situation is the same. If you like, I would be happy to give you the name of my pediatrican -- just email me through this list).
I know nothing about TB, but I have LOTS of experience with giving medincine over a prolonged period to my daughter (unfortunately). I'd be glad to give suggestions about giving your child the medication if you chose to go that route. Also, it is possible to get any medication flavored to make it tolerable to kids. A pharmacist on the East Coast developed very strong syrups that mask the flavor of practically any medicine after struggling to get lots of bad tasting medicine down his kid, who has epilepsy. There are pharmacies in California that will mix up your kid's medicine in this syrup and fedex them to you. I can find the number for one of them, if you'd like it. (I think these syrups are used at the pharmacy at Fresno Valley Children's Hospital.)
False positives can certainly happen with TB. But if you don't know where your child was exposed, it would be good to double check her possible sources, such as day care providers, other sitters, etc. I would get another opinion before starting on a course of isoniazide, because many TB strains are resistant to that drug. You can contact Children's Hospital in Oakland, where they have a specialist in pediatric TB, Dr. Ann McLaughlin. She is well known for her expertise and has access to other professionals who work in the area of TB, so could get others' input if necessary.
Which kind of TB test did your daughter take, the one we all had as kids (quick scratch on the surface) or the mantoux (needle under the skin, a more expensive test)? Dr. Ralph Berberich, my son's pediatrician, says that recent studies have shown that the old test has so many false positives and false negatives that it is worthless and shouldn't be used. The only reliable test, he says, is the mantoux. He cited medical organizations/agencies that shared his view. If your child had the discredited test, perhaps you don't need to be worrying how to get pills down a 5 year old's throat.
To the parent concerned with his or her child's positive TB test. Has your child ever traveled out of the country, and received an immunization shot? The reason I'm asking is because, coming from Peru as a child I was administered a shot that always counteracts with the antibody found in the TB shot. I have always shown to be positive, and after about 5-6 tests, chest X-Rays, and taking those nasty pills, my doctor decided it was not necessary for me to be exposed to such things. My body was purposely exposed to the causing agent, but never had the reaction. From this day on I will always test positive in my TB shots, but I was warned by my present doctor not to allow anyone to administer the TB shot because it was doing me more harm than good. I don't remember the name of the immunization that I was given, but I am sure that your pediatrician is aware of it. A doctor once told me that most native Filipinos and Latin Americans will show a positive TB result, only because of the immunization given to them at an early age. This in no way shows that they have ever had the infection.
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